Найкращі нейрохірурги з лікування медикаментозного лікування хвороби Паркінсона – ТОП-45 лікарів

Фахівець із глибокої стимуляції мозку (DBS). Провів понад 1000 успішних DBS та 1500 нейрохірургічних операцій.
Внесено до Книги рекордів Гіннеса за рекорд за найбільшою кількістю пацієнтів із DBS, зібраних в одному місці.
Проходив навчання у Німеччині, Іспанії, Великій Британії, Ізраїлі, Бельгії та США.

Гюлюмсер Кізілташ Токмак, доктор медичних наук, закінчила медичну школу Серрахпаша Стамбульського університету в 2002 році та закінчила ординатуру в неврологічній клініці Навчально-дослідної лікарні Окмейдані в 2008 році. Вона має ступінь магістра з електрофізіології Стамбульського університету, навчалася та працювала в різних сферах такі як ЕМГ, ЕЕГ, ПСГ, деменція, головний біль і запаморочення. Вона працювала в неврологічній клініці державної лікарні Агри, міжконтинентальній лікарні Гісар та лікарнях Медікал Парк.

He was born in 1978 in Prizren (Kosovo). After graduating from "Prizren Science High School" in 1996, he started his education at Pristina University Faculty of Medicine in 1996 and graduated from Kocaeli University Faculty of Medicine between 1999-2005. Between 2006-2011, he completed his specialty training in Neurology at Marmara University Faculty of Medicine, Department of Neurology. During her training, she was especially interested in electrophysiology, dementias and movement disorders. Between 2012-2013, she worked as a lecturer at Üsküdar University. Since 2013, she has been working as a Neurology specialist at NPIstanbul Brain Hospital. She has ongoing scientific studies in the field of neurology. He speaks fluent English, Serbian and Bosnian. In his free time, he is engaged in classical Turkish music.

Publications:

• Bilateral Thalamic Anaplastic Glioma: Case Report. Ibrahim Sun, Celal Salcini , Ayca Sun, Baran Yılmaz, Kadriye Agan. Marmara Medical Journal 2008, Volume 21, Issue 3, Page(s) 257-260
• Electrophysiology and Pathology Findings in a Case of Lafora. Ağan K, Erbaş B, Şalçini C, Uluç K, Günal D, Aktan S. 42nd National Neurology Congress, 2006
• Tumefactive MS: A Case Report. Deniz Borucu, Celal Şalçini, Betül Özdilek, Kayıhan Uluç, Neşe Tuncer Elmacı, Dilek İnce Günal. 43rd National Neurology Congress, 2007
• Creutzfeldt-Jacob Disease; Case Report with Radiologic and CSF Findings. Orhan Yılmaz, Celal Şalçini, Mesrure Köseoğlu, Kayıhan Uluç, İpek Midi, Neşe Tuncer,Önder Us, 43rd National Neurology Congress, 2007
• A Case of Tardive Dystonia Secondary to Low Dose Risperidone. Celal Şalçini, Kadriye Ağan, Dilek İnce Günal, 8th National Parkinson and Movement Disorders Congress, 2009
• Transcranial Direct Current Stimulation in a Patient With Schizoaffective Disorder Manic Episode. Gökben Hızlı Sayar, Celal Salcini, Ali Bayram, Gaye Kağan, Nevzat Tarhan, 2012
• Chapter XVI "SPINAL CORD DISEASES" of Merrit's Neurology Handbook, p:493-502 Uz.Dr. Kayıhan Uluç, Dr. Celal Şalçini, Translation editor O. Doğu, Güneş Tıp Kitapevleri, ISBN No: 978-975-277-207-6, Ankara 2009
• Neurophysiologic Approach to the Complex Organization in Spine: A study on F-wave duration and Cutaneous Silent Period in Primary Restless Legs Patients, İşak B., Uluç K., Şalçini C., Clinical Neuorphysyology, 2010

Neurosurgery Training: Gazi University, Department of Neurosurgery, 2011 

H index: 10, I10 Index: 12 Citations: 296

 Dr Mehmet Tonge has international and nationwide 32 publications, 12 book chapters, 92 oral and poster presentations and 41 invited lectures, mostly on Stereotactic and Functional Neurosurgery. 

Work & Training experience:

2004-2011: Gazi University, Department of Neurosurgery (Residency)

 2008: Zurich University Hospital, Department of Neurosurgery (Intraoperative MRI applications), Switzerland 

2008: Zurich University Hospital, Department of Neurosurgery: Microneurosurgery, white matter dissection, interventional neuroradiology courses, Switzerland 

2011 – 2012: Sinop Ataturk State Hospital, Neurosurgeon

 2012 – 2013: Cankiri State Hospital, Neurosurgeon 

2013 – 2014: Istanbul Medipol University, Department of Neurosurgery & Gamma Knife Center (Ass Prof) 

2013 – now: Maastricht University Neurosurgery & Neuroscience Department (Visiting scientist, PhDc) The Netherlands 

2014: Maastricht University, The Netherlands: Deep Brain Stimulation Fellowship 2014-2018: Istanbul Memorial Hospital Neurosurgery: Staff Neurosurgeon

 2016-2018: Istanbul Florence Nightingale Hospital (Consultant, Gamma Knife Center) 

2018-now: Istanbul Medipol University (Stereotactic & Functional Neurosurgery, Gamma Knife Center) Ass. Prof.) 

Dr Mehmet Tonge has completed 4-year cycle EANS (European Association of Neurosurgical Societies) Training courses. 

Clinical areas of interest:

 • Stereotactic & Functional Neurosurgery

 • Surgery for movement disorders

• * MR Guided Focused Ultrasound (MRgFUS)

 • Gamma Knife Radiosurgery 

• Surgery for pain & spasticity 

• Psychosurgery

Research areas of interest: 

• Deep brain stimulation

• * MR Guided Focused Ultrasound (MRgFUS)

 • Stereotactic radiosurgery 

Administrative duties:

 • Turkish Neurosurgical Society, Sterotactic & Functional Neurosurgery Section: Board member 2015- 2017 

• Turkish Neurosurgical Society, Sterotactic & Functional Neurosurgery Section: Board member (Secretary) 2017-2019

 • Turkish Skull Base Society: Board member 2016-2018

 • Turkish Skull Base Society: Supervisory board member 2018-2020

 • Deep Brain Stimulation and Movement Disorders Surgery Society: Executive Board Member, (Accountant) 2023-still 

Memberships: 

• WSSFN (World Stereotactic & Functional Neurosurgery Society) 

• ESSFN (European Stereotactic & Functional Neurosurgery Society)

 • Deep Brain Stimulation and Movement Disorders Surgery Society

 • Deep Brain Stimulation Society 

• International Stereotactic Radiosurgery Society 

• Leksell Gamma Knife Society 

• EANS (European Association of Neurosurgical Societies) 

• Turkish Neurosurgical Society

• Turkish Skull Base Society

Sample Publications: 

1. Tonge M. Technological developments in electric based DBS. Deep Brain Stimulation 2024 4(36-41) DOI: https://doi.org/10.1016/j.jdbs.2023.12.001 

2. Akgul E, Onan HB, Islek I, Tonge M, Durmus Y, Barburoglu M, Azizova A, Erol C, Hakyemez B, Sencer S, Aydin K, Arat A. Flow diverter stents in the treatment of recanalized intracranial aneurysms. Interv Neuroradiol. 2021 Aug;27(4):481-489. doi: 10.1177/1591019921990507. Epub 2021 Jan 28. PMID: 33509011; PMCID: PMC8580529. 

3. Mulders AEP, Temel Y, Tonge M, Schaper FLWVJ, van Kranen-Mastenbroek V,Ackermans L, Kubben P, Janssen MLF, Duits A. The association between surgical characteristics and cognitive decline following deep brain stimulation of the subthalamic nucleus in Parkinson's disease. Clin Neurol Neurosurg. 2021 Jan;200:106341. doi: 10.1016/j.clineuro.2020.106341. Epub 2020 Nov 3. PMID: 33160716. 

4. Wetzelaer P, Vlis T, Tonge M, Ackermans L, Kubben P, Evers S, Kocabicak E, Temel Y. Management of Hardware Related Infections after DBS Surgery: A Cost Analysis. Turk Neurosurg. 2018;28(6):929- 933. doi: 10.5137/1019-5149.JTN.21511-17.1. PMID: 29465741. 

5. Bedirli N, Emmez G, Ünal Y, Tönge M, Emmez H. Effects of positive end- expiratory pressure on intracranial pressure during pneumoperitoneum and Trendelenburg position in a porcine mode. Turk J Med Sci. 2017 Nov 13;47(5):1610-1615. doi: 10.3906/sag-1609-17. PMID: 29152942. 

6. Sari R, Tonge M, Bolukbasi FH, Onoz M, Baskan O, Silav G, Elmaci I. Management of Failed Cranioplasty. Turk Neurosurg. 2017;27(2):201-207. doi: 10.5137/1019-5149.JTN.15395-15.0. PMID: 27593759. 

7. Tonge M, Kocabicak E, Ackermans L, Kuijf M, Temel Y. Final Electrode Position in Subthalamic Nucleus Deep Brain Stimulation Surgery: A Comparison of Indirect and Direct Targeting Methods. Turk Neurosurg. 2016;26(6):900-903. doi: 10.5137/1019-5149.JTN.13739-14.1. PMID: 27337232. 

8. Tonge M, Ackermans L, Kocabicak E, van Kranen-Mastenbroek V, Kuijf M, Oosterloo M, Kubben P, Temel Y. A detailed analysis of intracerebral hemorrhages in DBS surgeries. Clin Neurol Neurosurg. 2015 Dec;139:183-7. doi: 10.1016/j.clineuro.2015.10.017. Epub 2015 Oct 23. PMID: 26513430. 

9. Silav G, Bölükbaşı FH, Özek E, Tönge M, Önöz M, Elmacı İ. A Simple Technique for Bone Storage after Decompressive Craniectomy in Children. Pediatr Neurosurg. 2015;50(3):161-4. doi: 10.1159/000381748. Epub 2015 May 14. PMID: 25998533. 

10. Yilmaz MB, Donmez H, Tonge M, Senol S, Tekiner A. Vertebrojugular arteriovenous fistula and pseudoaneurysm formation due to penetrating vertebral artery injury: case report and review of the literature. Turk Neurosurg. 2015;25(1):141-5. doi: 10.5137/1019-5149.JTN.8247-13.1. PMID: 25640560. 

11. Kurt G, Tönge M, Çeltıkçı E, Çapraz I, Serdaroğlu A, Bılır E. Surgery for intractable temporal lobe epilepsy: experience of a single institution. Turk J Med Sci. 2014;44(5):866-70. doi: 10.3906/sag-1307- 30. PMID: 25539559. 

12. Yılmaz MB, Tönge M, Emmez H, Kaymaz F, Kaymaz M. Neuroprotective effects of quetiapine on neuronal apoptosis following experimental transient focal cerebral ischemia in rats. J Korean Neurosurg Soc. 2013 Jul;54(1):1-7. doi: 10.3340/jkns.2013.54.1.1. Epub 2013 Jul 31. PMID: 24044072; PMCID: PMC3772279. 

13. Yilmaz MB, Egemen E, Tonge M, Kaymaz M. Transoral protrusion of a peritoneal catheter due to gastric perforation 10 years after a ventriculoperitoneal shunting: case report and review of the literature. Turk Neurosurg. 2013;23(2):285-8. doi: 10.5137/1019-5149.JTN.4904-11.1. PMID: 23546921. 

14. Omerhodzic I, Tonge M, Matos B, Musabeliu E, Raspanti C, Ferdinandov D, Galimova R, Muroi C, Balik V, Kursumovic A. Neurosurgical training programme in selected European countries: from the young neurosurgeons' point of view. Turk Neurosurg. 2012;22(3):286-93. doi: 10.5137/1019- 5149.JTN.5133-11.0. PMID: 22664994. 

15. Ergun E, Kurt G, Tonge M, Aytar H, Tas M, Baykaner K, Ceviker N. Effects of phenytoin sodium on dura mater healing in a rat model of CSF leakage. Turk Neurosurg. 2011;21(4):471-6. PMID: 22194102. 

16. Emmez H, Tonge M, Tokgoz N, Durdag E, Gonul I, Cevıker N. Radiological and histopathological comparison of microporous polysaccharide hemospheres and oxidized regenerated cellulose in the rabbit brain: a study of efficacy and safety. Turk Neurosurg. 2010 Oct;20(4):485-91. doi: 10.5137/1019- 5149.JTN.3300-10.2. PMID: 20963698. 

17. Emmez H, Yildirim Z, Kale A, Tönge M, Durdağ E, Börcek AO, Uçankuş LN, Doğulu F, Kiliç N, Baykaner MK. Anti-apoptotic and neuroprotective effects of α-lipoic acid on spinal cord ischemiareperfusion injury in rabbits. Acta Neurochir (Wien). 2010 Sep;152(9):1591-600; discussion 1600-1. doi: 10.1007/s00701-010-0703-9. Epub 2010 Jun 10. PMID: 20535507. 

18. Kurt G, Tonge M, Börcek AO, Karahacioglu E, Gurel O, Baykaner K, Ceviker N, Aykol S. Fractionated gamma knife radiosurgery for optic nerve tumors: a technical report. Turk Neurosurg. 2010 Apr;20(2):241-6. doi: 10.5137/1019-5149.JTN.1681-09.3. PMID: 20401852. 

19. Emmez H, Kale A, Tönge M, Cakir A, Ceviker N. Two meningiomas with different histological grades in the same patient. Case report. Neurol Med Chir (Tokyo). 2010;50(8):686-8. doi: 10.2176/nmc.50.686. PMID: 20805656.

Education and Expertise

1998 - 2005 - Marmara University Faculty of Medicine

1998 - 2005 - Marmara University, Faculty of Medicine, Department of Neurosurgery, Istanbul

(Head of the Department: Prof Dr Türker KILIÇ)

2011 - 2012 - Yale School of Medicine, New Haven, CT, USA (Director: Murat Günel MD. PhD., Professor of Neurosurgery)Cerebrovascular Research Fellowship

Professional Memberships

2014 + Turkish Neurosurgery Association

2017 + Turkish Spine Association

2018 + AOSpine

Awards

Turkish Neurosurgery Society 31st Scientific Congress “Prof. Dr. Hamit Ziya Gökalp Young Neurosurgeon Encouragement First Prize”, Antalya, 2017.

Courses and Certificates

1. Member of the Organizing Committee; 12. National Neuroscience Congress, Bahçeşehir University, 28-31 May 2014

2. Member of the Organizing Committee; 11. ASNO 'Skull-base Anatomy Course', 11-14 September 2014, Istanbul

3. Instructor / Member of the Organizing Committee; Neurosurgery Course Series – 4 /Prof. Dr. Evandro de Oliveira Skull Base Course 2, Prof. Rhoton Anatomy Lab BAU Faculty of Medicine, Istanbul, 2015.

4. Member of the Organizing Committee; International Deep Brain Stimulation Surgery Microelectrode Recording Cadaver Course, Rhoton Anatomy Lab BAU Faculty of Medicine, 6-7 February 2015 Istanbul.

5. Organization Officer; TND Istanbul Meetings, Istanbul, 2015-2016

Education and Specialization:

• Medical Degree: Istanbul University Cerrahpaşa Faculty of Medicine (1991-1998)
• Specialization in Neurosurgery: Karadeniz Technical University Faculty of Medicine (1999-2005)
• Associate Professorship: (2015)
• Professorship: (2020)

Professional Experience:

• 2007-2008: Ankara GATA
• 2009-2011: Özel Ordu Medical Park Hospital
• 2011-2013: Ankara Keçiören Training and Research Hospital
• 2013-2015: Giresun University Faculty of Medicine
• 2014: Clinical Observer at Helsinki University Central Hospital
• 2015-2023: Karadeniz Technical University Faculty of Medicine
• Current Position: Neurosurgeon at VM Medical Park Pendik Hospital

Areas of Expertise:

• Brain Aneurysm and Repair
• Brain Tumor/Cancer Surgery
• Spinal Canal Stenosis Surgery
• Lumbar and Cervical Disc Herniation
• Spinal Cord Surgery
• Minimally Invasive Neurosurgery
• Pediatric Neurosurgery
• Congenital Anomalies

Research and Publications: Prof. Dr. Arslan has numerous publications in prestigious journals, covering topics such as the treatment of brain and spinal tumors, innovative neurosurgical techniques, and outcomes of neurosurgical interventions. His work includes studies on brain ischemia/reperfusion injury, spinal cord ischemia, and various other neurosurgical conditions.

Professional Memberships:

• Turkish Neurosurgery Association
• Turkish Society of Neurological Surgery

2002-2007 Istanbul University Istanbul Faculty of Medicine Department of Brain and Nerve Surgery

1988-1995 Trakya University Faculty of Medicine

2015- Atlas University Medicine Hospital

2014-2015 Private Pendik Yüzyıl Hospital Brain and Neurosurgery Clinic

2009-2014 Medicine Hospital Brain and Neurosurgery Clinic

2009-2009 Nisa Hospital Brain and Neurosurgery Clinic

2007-2009 Mardin State Hospital Brain and Neurosurgery Clinic

2002-2007 Istanbul University Istanbul Faculty of Medicine Brain and Neurosurgery

1997-2001 Enez Health Center and Enez State Hospital

Cervical, Thoracic and Lumbar Disc Surgery (endoscopic/microsurgery)

Far lateral (non-canal) lumbar disc surgery (lateral microsurgical approach)

Neurovascular surgery

Cerebrovascular diseases (vascular diseases of the brain)

Aneurysms

Arteriovenous malformations

Cavernomas

Neuro-oncological surgery

Brain tumors

Glial tumors

Meningiomas

Pituitary gland tumors

Metastatic brain tumors

Skull base tumors

Pontocerebellar angle tumors

Pineal tumors

Intraventricular tumors

Spinal disease surgery

Cervical, thoracic and lumbar spine fractures

Spine and spinal cord tumors

Scoliosis

Degenerative spine diseases

Peripheral nerve disease surgery

Peripheral nerve tumors

Entrapment neuropathies

Carpal tunnel syndrome

Ulnar groove syndrome

Tarsal tunnel syndrome

Functional neurosurgery and pain surgery

Trigeminal neuralgia

Microvascular decompression

Epilepsy surgery

Spasticity surgery

Epiduroscopic interventions

Hydrocephalus surgeries

Endoscopic 3rd ventriculostomy

VP shunt surgeries

LP shunt surgeries

Developmental anomalies

Meningomyelocele

Tethered cord syndrome

Arachnoid cyst

Craniosynostosis surgeries

Chiari malformation

Head trauma

Subdural hematomas

Intracerebral hematomas

Article published in internationally refereed journals

Cansever T, Civelek E, Sencer A, Karasu A, Kiris T, Hepgül K, Can H, Canbolat A: Spinal cavernous malformations: a report of 5 cases. Surg Neurol Jun 69 

Effects of combined and individual use of N-methyl-D aspartate receptor antagonist magnesium sulphate and caspase-9 inhibitor z-LEDH-fmk experimental spinal cord injury. A.Sencer, A.Aydoseli, Y.Aras, M.Osman Akçakaya, C.Gömleksiz, H.Can, A.Canbolat. Turkısh Joumal of Trauma&Emergency Surgery 2013

Aydoseli A, Can H, Aras Y, Sabanci PA, Akcakaya MO, Unal OF. Memantine and Q-VD-OPh Treatments in Experimental Spinal Cord Injury: Combined Inhibition of Necrosis and Apoptosis. Turk Neurosurg. 2016

Can H, Kircelli A, Kavadar G, Civelek E, Cansever T, Aydoseli A, Onal MB, Yilmaz C. Lumbosacral Conjoined Root Anomaly: Anatomical Considerations of Exiting Angles and Root Thickness. Turk Neurosurg. 2017

Kırcelli A, Özel Ö, Can H, Sarı R, Cansever T, Elmacı İ. Is the presence of linear fracture a predictor of delayed posterior fossa epidural hematoma? Ulus Travma Acil Cerrahi Derg. 2016 Jul

Kavadar G, Demircioğlu DT, Can H, Emre TY, Civelek E, Senyigit A. The clinical factors associated with benefit finding of complementary medicine use in patients with back pain: A cross-sectional study with cluster analysis. J Back Musculoskelet Rehabil. 2017

Ozer AF, Suzer T, Can H, Falsafi M, Aydin M, Sasani M, Oktenoglu T. Anatomic Assessment of Variations in Kambin’s Triangle: A Surgical and Cadaver Study. World Neurosurg. 2017 Apr

Can H, Aydoseli A, Gömleksiz C, Göker B, Altunrende ME, Dolgun M, Sencer A. Combined and individual use of pancaspase inhibitor Q-VD-OPh and NMDA receptor antagonist riluzole in experimental spinal cord injury. Ulus Travma Acil Cerrahi Derg. 2017

Gomleksiz C, Erbulut DU, Can H, Kodigudla MK, Kelkar AV, Kasapoglu E, Ozer AF, Goel VK. A new lumbar fixation device alternative to pedicle-based stabilization for lumbar spine: In vitro cadaver investigation. J Spinal Cord Med. 2018 Jul 16:1-8.

Aydoseli A, Özgen U, Akgül T, Orhan EK, Adıyaman AE, Can H, Karadağ C. Subacute Traumatic Ascending Myelopathy in a 28-year-old man: A rare case. World Neurosurg. 2019 Apr 28

Article published in national refereed journals

1) Intracranial Hemangioblastomas: Clinical Evaluation of 32 Patients T. Cansever, A. Karasu, K. Hepgül, H. Can, A. Sencer Turkish Neurosurgical Journal 2007, Volume:17 

2) Halil Can, Müge Dolgun, Utku Özgen, Cengiz Gömleksiz, Furkan Diren, Aydın Aydoseli, Yavuz Aras, Altay Sencer. Microsurgical Results in Vestibular Schwannoma Patients; Retrospective Clinical Study. JAREM 2019

3) Furkan Diren , Özcan Gayretli , Halil Can , İlke Ali Gürses , Orhan Barlas. Examination of Pons-Cerebellum Cisterna Anatomy with Endoscopic Retrosigmoid Suboccipital Approach: Cadaver Study. JAREM 2019

Jefe de Enseñanza Hospital Regional de Puerto Vallarta  

2020-2023

Encargada de expediente clínico en Hospital Regional de Puerto Vallarta 2 meses 2020  

Médico general en consultorio médico particular  

2015-2022  

Medico a cargo de clínica para control de peso  

2013-2014  

Asistente médico en clínica dermatológica

2008-2013 

 Asistente Medico en procedimientos Dermatológicos.  

 Asistente Medico en procedimientos quirúrgicos mínimo invasivos  

 Operación de máquina de laser fraccionado - IPIXEL-ER y  

rejuvenecimiento facial con  IPL.  

 Experiencia en depilación láser con Luz Pulsada Intensa  y  

radiofrecuencia  

 Experiencia con cavitación ultrasónica  

 Experiencia con máquina de fototerapia con luz ultravioleta (UV) para el  

tratamiento de psoriasis y vitíligo.    

 Experiencia asistiendo en procedimientos de Botox y Rellenos.  

 Biomagneta certificada por Instituto superior de biomagnetismo  

medico ISAAC GOIZ DURAN  

 Experiencia en expediente clínico    

 Capacitación en formación continua y desarrollo profesional docent