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injection is typical; repeat injection depends on protocol."},"success":{"metric":"Patients with meaningful knee pain relief","value":65,"unit":"percent","horizon":"6-12 months","population":"Adults with mild to moderate knee osteoarthritis; bone marrow aspirate concentrate or adipose-derived cells","evidence_status":"limited"},"techniques":[{"name":"Bone marrow aspirate concentrate injection","suits_whom":"Adults with knee osteoarthritis; marrow harvested from iliac crest under local anesthetic","recovery":"Same-day discharge; harvest-site puncture soreness for several days."},{"name":"Adipose-derived stromal cell injection","suits_whom":"Adults with knee osteoarthritis; fat harvested from abdomen under local anesthetic","recovery":"Same-day discharge; harvest-site bruising and soreness for several days."}],"treatment_conditions":["outpatient"],"treatment_duration_hours":{"min":1.5,"max":3,"unit":"hours","qualifier":"Includes harvest, cell processing and injection; varies with cell source and processing method."},"initial_assessment_documents":["Knee MRI report","Knee X-ray report","Orthopedic diagnosis or clinic notes","List of blood thinners","Previous knee injections or surgery records"],"travel_trips":{"min":1,"max":2,"one_trip_possible":true,"qualifier":"Usually a single-session cell harvest and injection with a 1-3 day stay; some protocols add a repeat injection."},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Ask how your aftercare will be coordinated","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"Ensure you're clear about how your aftercare will be coordinated.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"C2","text":"Ask whether follow-up care is scheduled at the same facility as the 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have 2 consultations with the surgeon treating you before any surgery.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F2","text":"Medical questions are answered by sales or travel-agent staff, not the clinician","scope":"treatment_abroad","source":{"url":"https://travelhealthpro.org.uk/factsheet/59/travelling-for-treatment-medical-tourism","host":"travelhealthpro.org.uk","quote":"Medical advice from an administrator, a travel agent, or member of a sales team is not acceptable.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F3","text":"An advert or information that guarantees complete success should raise concerns","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Any advert or information that guarantees complete success should raise 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swollen or red skin over the affected joint","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"W4","text":"A high temperature (fever)","urgency":"contact_clinic","general":true,"source":{"url":"https://www.nhs.uk/conditions/septic-arthritis/","host":"nhs.uk","quote":"a high temperature (fever)","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"take_home":{"status":"ok","items":[{"id":"T1","text":"Lets the home doctor compare imaging with later results","document":"scan and x-ray copies","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Remember to ask for copies of all your treatment records, including prescriptions, scans and x-rays before you leave.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"T2","text":"Home doctor needs the clinic's follow-up 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