{"key":"op_1430_CN","page":{"url":"https://ua.bookimed.com/clinics/country=china/procedure=stem-cell-treatment-for-alzheimer-s-disease/","procedure":{"id":1430,"slug":"stem-cell-treatment-for-alzheimer-s-disease","name":"Лікування хвороби Альцгеймера стовбуровими клітинами","name_forms":{"plural":{"status":"missing","reason":"not_collected"},"genitive":{"status":"missing","reason":"not_collected"}},"type":"therapy","grammar_number":{"status":"missing","reason":"not_collected"},"parent_id":"stem-cells","family_attribute":{"status":"missing","reason":"not_collected"}},"country":{"id":203,"iso":"CN","name":"Китай"},"currency":"USD","data_date":{"status":"missing","reason":"not_collected"}},"pages":{"clinics_url":"https://ua.bookimed.com/clinics/country=china/procedure=stem-cell-treatment-for-alzheimer-s-disease/","cost_url":"https://ua.bookimed.com/clinics/country=china/procedure=stem-cell-treatment-for-alzheimer-s-disease/cost/","best_url":{"status":"missing","reason":"template not live"}},"price":{"from":15800,"to":26000,"avg":{"value":15800,"method":"median","source":"offers"},"us":{"from":6500,"to":14000},"uk":{"from":9500,"to":19500},"by_technique":{"status":"missing","reason":"not_collected"},"by_city":[{"city":"Цюнхай","from":15800},{"city":"Шанхай","from":12000}],"per_unit":{"status":"missing","reason":"not_collected"},"factors":{"status":"missing","reason":"not_collected"},"tiers":{"source":"offers","items":[{"tier":"standard","min":15800,"max":15800,"median":15800,"count":1}]},"comparison":[{"country_iso":"UA","from":11100,"to":15500},{"country_iso":"FR","from":9000,"to":18000},{"country_iso":"GB","from":9500,"to":19500},{"country_iso":"US","from":6500,"to":14000},{"country_iso":"IL","from":14000,"to":24000},{"country_iso":"TR","from":11900,"to":12000},{"country_iso":"MX","from":9000,"to":20000},{"country_iso":"DE","from":9000,"to":16500},{"country_iso":"CA","from":6500,"to":18000},{"country_iso":"AE","from":9000,"to":21000},{"country_iso":"TH","from":7200,"to":19000},{"country_iso":"PL","from":6500,"to":12500},{"country_iso":"KR","from":32900,"to":{"status":"missing","reason":"not_collected"}},{"country_iso":"CZ","from":6500,"to":11000},{"country_iso":"AT","from":9500,"to":15500},{"country_iso":"ES","from":6500,"to":12500},{"country_iso":"IT","from":9500,"to":17500},{"country_iso":"AU","from":9000,"to":19000},{"country_iso":"IN","from":6500,"to":12500},{"country_iso":"MY","from":6500,"to":13500},{"country_iso":"VN","from":9000,"to":20000},{"country_iso":"BR","from":8000,"to":12000}],"base_country":"US","base_is_fallback":false},"savings":{"pct":-143,"variant":"more_expensive"},"package":{"included":["24-hr nurse services","VIP transfer (premium vehicle service, all transfers between airport, hotel and clinic)"],"excluded":["Accommodation is not included"],"extra_charges":{"status":"missing","reason":"not_collected"}},"clinics":{"count":2,"items":[{"id":7994,"name":"Boao International Medical Center","city":"Qionghai","rating":{"status":"missing","reason":"not_collected"},"reviews_count":{"status":"missing","reason":"not_collected"},"accreditations":{"status":"missing","reason":"not_collected"},"rank":1,"has_procedure":true,"why_ranked":{"status":"missing","reason":"not_collected"},"bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":[{"id":"6a5fda82b360eaae330ecd22","price":15800,"nights":30,"included":["24-hr nurse services","VIP transfer (premium vehicle service, all transfers between airport, hotel and clinic)"],"excluded":["Accommodation is not included"],"other_services":"Indications: 1. Sequelae of Cerebral Infarction 2. Sequelae of Cerebral Hemorrhage 3. Sequelae of Traumatic Brain Injury 4. Spinal Cord Injury 5. Parkinson's Disease 6. Alzheimer's Disease 7. Neurological Injury 8. Neurogenetic Disorders 9. Amyotrophic Lateral Sclerosis (ALS), etc. Reference Fee Schedule (Settled in USD) Estimated Cost: $15,800 (A single stem cell treatment) (Excludes international airfare, lodging, meals, personal expenses, and unlisted unexpected medical expenses) Procedure: 1. Preoperative Preparation: Complete blood count, liver and kidney function, coagulation profile, four infectious disease screenings, intracranial pressure measurement, diffusion tensor imaging (DTI), etc. 2. Positioning and Localization: Lateral decubitus position with knees drawn to chest, localize L3-L4 or L4-L5 intervertebral space 3. Anesthesia and Puncture: Local infiltration anesthesia, minimally invasive puncture into subarachnoid space 4. Decompression: Slowly release 3-5ml of cerebrospinal fluid for moderate decompression 5. Medication Infusion: Slow and steady injection of nerve repair and regeneration compound preparation 6. Postoperative Care: Supine position without pillow for 6-8 hours after needle removal, fasting for 2 hours, close monitoring of vital signs and consciousness Core Mechanism of Action: 1. Intrathecal delivery directly into cerebrospinal fluid circulation, acting directly on damaged brain parenchyma and spinal cord conduction tracts 2. Promotes activation of glial cells around hematoma, accelerates hematoma absorption and clearance of metabolic products 3. Reduces secondary cerebral edema, inhibits inflammatory cascade, protects surviving neurons 4. Repairs and regenerates damaged nerve fibers, reconstructs neural conduction pathways 5. Regulates central immunity, improves cerebral microcirculation, prevents delayed neuronal injury"}]},{"id":8264,"name":"Panacee International Hospital Qinhuangdao","city":"Qinhuangdao","rating":{"status":"missing","reason":"not_collected"},"reviews_count":{"status":"missing","reason":"not_collected"},"accreditations":{"status":"missing","reason":"not_collected"},"rank":2,"has_procedure":true,"why_ranked":{"status":"missing","reason":"not_collected"},"bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":{"status":"missing","reason":"no_offers"}}]},"doctors":{"count":{"status":"missing","reason":"not_collected"},"languages":{"status":"missing","reason":"not_collected"}},"cities":[{"id":2715,"slug":"qionghai","name":"Цюнхай","clinics_count":1,"price_from":15800,"profile":{"city_type":"County-level city in Hainan, China","access":["Qionghai Boao Airport (BAR), 12 km from downtown"],"sources":["https://en.wikipedia.org/wiki/Qionghai","https://www.travelchinaguide.com/cityguides/hainan/qionghai-boao-airport.htm"],"checked_at":"2026-11-03","status":"ok"}},{"id":2015,"slug":"shanghai","name":"Шанхай","clinics_count":{"status":"missing","reason":"not_collected"},"price_from":12000,"profile":{"city_type":"Most populous city in China","access":["Pudong Airport (PVG), 30 km from the city center","Hongqiao Airport (SHA), 13 km from downtown"],"sources":["https://en.wikipedia.org/wiki/Shanghai","https://en.wikipedia.org/wiki/Shanghai_Pudong_International_Airport","https://en.wikipedia.org/wiki/Shanghai_Hongqiao_International_Airport"],"checked_at":"2026-11-03","status":"ok"}}],"offers":{"active":1,"active_with_related":1,"hospital_nights_median":30,"days_in_country_median":{"status":"missing","reason":"fewer than 10 offers with hotel days"},"top_offers":[{"id":"6a5fda82b360eaae330ecd22","clinic_id":7994,"clinic_listed":true,"price":15800,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["24-hr nurse services","VIP transfer (premium vehicle service, all transfers between airport, hotel and clinic)"],"excluded":["Accommodation is not included"],"other_services":"Indications: 1. Sequelae of Cerebral Infarction 2. Sequelae of Cerebral Hemorrhage 3. Sequelae of Traumatic Brain Injury 4. Spinal Cord Injury 5. Parkinson's Disease 6. Alzheimer's Disease 7. Neurological Injury 8. Neurogenetic Disorders 9. Amyotrophic Lateral Sclerosis (ALS), etc. Reference Fee Schedule (Settled in USD) Estimated Cost: $15,800 (A single stem cell treatment) (Excludes international airfare, lodging, meals, personal expenses, and unlisted unexpected medical expenses) Procedure: 1. Preoperative Preparation: Complete blood count, liver and kidney function, coagulation profile, four infectious disease screenings, intracranial pressure measurement, diffusion tensor imaging (DTI), etc. 2. Positioning and Localization: Lateral decubitus position with knees drawn to chest, localize L3-L4 or L4-L5 intervertebral space 3. Anesthesia and Puncture: Local infiltration anesthesia, minimally invasive puncture into subarachnoid space 4. Decompression: Slowly release 3-5ml of cerebrospinal fluid for moderate decompression 5. Medication Infusion: Slow and steady injection of nerve repair and regeneration compound preparation 6. Postoperative Care: Supine position without pillow for 6-8 hours after needle removal, fasting for 2 hours, close monitoring of vital signs and consciousness Core Mechanism of Action: 1. Intrathecal delivery directly into cerebrospinal fluid circulation, acting directly on damaged brain parenchyma and spinal cord conduction tracts 2. Promotes activation of glial cells around hematoma, accelerates hematoma absorption and clearance of metabolic products 3. Reduces secondary cerebral edema, inhibits inflammatory cascade, protects surviving neurons 4. Repairs and regenerates damaged nerve fibers, reconstructs neural conduction pathways 5. Regulates central immunity, improves cerebral microcirculation, prevents delayed neuronal injury","is_package":true}],"packages":[{"id":"6a5fda82b360eaae330ecd22","clinic_id":7994,"clinic_listed":true,"price":15800,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["24-hr nurse services","VIP transfer (premium vehicle service, all transfers between airport, hotel and clinic)"],"excluded":["Accommodation is not included"],"other_services":"Indications: 1. Sequelae of Cerebral Infarction 2. Sequelae of Cerebral Hemorrhage 3. Sequelae of Traumatic Brain Injury 4. Spinal Cord Injury 5. Parkinson's Disease 6. Alzheimer's Disease 7. Neurological Injury 8. Neurogenetic Disorders 9. Amyotrophic Lateral Sclerosis (ALS), etc. Reference Fee Schedule (Settled in USD) Estimated Cost: $15,800 (A single stem cell treatment) (Excludes international airfare, lodging, meals, personal expenses, and unlisted unexpected medical expenses) Procedure: 1. Preoperative Preparation: Complete blood count, liver and kidney function, coagulation profile, four infectious disease screenings, intracranial pressure measurement, diffusion tensor imaging (DTI), etc. 2. Positioning and Localization: Lateral decubitus position with knees drawn to chest, localize L3-L4 or L4-L5 intervertebral space 3. Anesthesia and Puncture: Local infiltration anesthesia, minimally invasive puncture into subarachnoid space 4. Decompression: Slowly release 3-5ml of cerebrospinal fluid for moderate decompression 5. Medication Infusion: Slow and steady injection of nerve repair and regeneration compound preparation 6. Postoperative Care: Supine position without pillow for 6-8 hours after needle removal, fasting for 2 hours, close monitoring of vital signs and consciousness Core Mechanism of Action: 1. Intrathecal delivery directly into cerebrospinal fluid circulation, acting directly on damaged brain parenchyma and spinal cord conduction tracts 2. Promotes activation of glial cells around hematoma, accelerates hematoma absorption and clearance of metabolic products 3. Reduces secondary cerebral edema, inhibits inflammatory cascade, protects surviving neurons 4. Repairs and regenerates damaged nerve fibers, reconstructs neural conduction pathways 5. Regulates central immunity, improves cerebral microcirculation, prevents delayed neuronal injury","is_package":true}],"related_packages":{"status":"missing","reason":"not_collected"},"other_packages":{"status":"missing","reason":"not_classified"}},"medical":{"indications":["Early-stage Alzheimer's disease","Mild cognitive impairment with Alzheimer's pathology"],"contraindications":["Active infection","Active or past malignancy","Severe dementia","Bleeding disorders or anticoagulant therapy","Pregnancy or breastfeeding","Severe cardiac, renal or hepatic disease","Immunosuppression","Allergy to product components","Unstable psychiatric or medical condition"],"operation_hours":{"min":2,"max":6,"unit":"hours","qualifier":"Infusion or lumbar puncture plus several hours of post-dose observation per session."},"anesthesia":["none","local"],"sessions_or_stages":{"sessions":{"min":1,"max":3,"unit":"visits","qualifier":"Usually one course of IV or intrathecal doses in one stay; some clinics repeat after 3-6 months."},"stages":[{"code":"assessment_screening","label":"Assessment and screening","after":{"min":0,"max":0,"unit":"days","qualifier":"Done on arrival before treatment."}},{"code":"cell_administration","label":"IV or intrathecal cell administration","after":{"min":1,"max":3,"unit":"days","qualifier":"Doses given within one stay."}},{"code":"repeat_course","label":"Optional repeat course","after":{"min":90,"max":180,"unit":"days","qualifier":"Only if the clinic protocol repeats dosing."}}],"qualifier":"Typical protocol is one course within a single stay."},"hospital_nights":{"value":30,"source":"offers","parsed_details":{"min":2,"max":5,"unit":"nights","qualifier":"Nights until post-dose observation and flight clearance; longer if headache persists."}},"treatment_conditions":["outpatient"],"rehabilitation_days":{"min":3,"max":7,"unit":"days","qualifier":"Time to ordinary function after administration; cognitive rehabilitation, if used, continues separately."},"fly_home_after_days":{"min":2,"max":5,"unit":"days","qualifier":"After intrathecal dosing, clearance depends on headache resolution and clinician assessment."},"back_to_work_days":{"min":3,"max":7,"unit":"days","qualifier":"Most patients are retired; return to usual activities depends on route and post-procedure headache or fatigue."},"exercise_resume_weeks":{"min":1,"max":2,"unit":"weeks","qualifier":"Light activity resumes first; strenuous exercise waits until puncture-site and symptom resolution."},"final_result_months":{"min":3,"max":12,"unit":"months","qualifier":"Trials assess cognitive outcomes at 3-12 months; no proven effect."},"result_longevity":"No proven benefit or durability has been established. Any reported effect in trials is variable and often transient, with some clinics repeating courses after 3-6 months.","main_risks":["Post-lumbar puncture headache, back pain or low-grade fever","Infection, immune or allergic reactions, and route-related events (intrathecal, intravenous).","Unregulated clinics may use poorly characterized, contaminated or unproven products.","Theoretical abnormal cell growth; not shown in Alzheimer's trials."],"complication_rate_pct":{"min":10,"max":30,"unit":"percent","qualifier":"Any adverse event within 30 days, mostly transient headache, fever, back pain; serious events under 2%"},"revision_rate_pct":{"min":0,"max":0,"unit":"percent","qualifier":"No corrective revision is typical; repeat dosing is counted under sessions or stages."},"success":{"metric":{"status":"missing","reason":"not_collected"},"value":{"status":"missing","reason":"not_collected"},"horizon":{"status":"missing","reason":"not_collected"},"source":{"status":"missing","reason":"not_collected"},"evidence_status":"not_proven"},"scars":"No visible scar; only a small needle puncture mark at the lumbar or IV site. If cells are harvested by liposuction or marrow aspiration, a tiny puncture mark remains.","pain":"Mild and brief: lumbar puncture or IV site discomfort. Post-puncture headache, back pain or low-grade fever can occur for 1-3 days.","preparation":["Neurology review of diagnosis and stage","Baseline MMSE or MoCA testing","Brain MRI or CT review","Blood tests and infection screening","Review and adjust anticoagulants","Medication list reviewed","Caregiver or legal guardian consent"],"recovery_timeline":[{"phase":"Day 0-1","description":"Cell administration followed by observation for reactions, headache or fever.","restrictions":["Lie flat if intrathecal","Avoid driving","Stay hydrated"]},{"phase":"Days 2-7","description":"Mild fatigue or headache may settle; monitoring of neurological status continues.","restrictions":["No strenuous activity","Caregiver supervision"]},{"phase":"Weeks 2-4","description":"Return to normal routine; early follow-up checks.","restrictions":["Report fever, severe headache or new neurological symptoms"]},{"phase":"Months 3-6","description":"Cognitive reassessment to evaluate any change.","restrictions":{"status":"missing","reason":"not_collected"}}],"follow_up_visits":[{"purpose":"wound_check","requirement":"routine","after":{"min":1,"max":7,"unit":"days","qualifier":"Check for headache, fever or puncture-site problems."}},{"purpose":"assessment","requirement":"routine","after":{"min":30,"max":90,"unit":"days","qualifier":"Cognitive testing such as MMSE or MoCA."}},{"purpose":"result_review","requirement":"routine","after":{"min":90,"max":180,"unit":"days","qualifier":"Repeat cognitive testing and possible imaging."}}],"sources":{"status":"missing","reason":"not_collected"},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Check whether the treatment is approved for Alzheimer's disease","scope":"procedure","source":{"url":"https://www.fda.gov/vaccines-blood-biologics/consumers-biologics/consumer-alert-regenerative-medicine-products-including-stem-cells-and-exosomes","host":"fda.gov","quote":"None of these products have been approved to treat any neurological disorder, such as multiple sclerosis, amyotrophic lateral sclerosis (ALS; Lou Gehrig’s disease), Alzheimer’s disease, Parkinson’s disease, epilepsy, or stroke.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"C2","text":"Check that the product is offered only within a clinical trial, since charges outside one suggest an illegal product","scope":"treatment_type","source":{"url":"https://www.fda.gov/vaccines-blood-biologics/consumers-biologics/important-patient-and-consumer-information-about-regenerative-medicine-therapies?","host":"fda.gov","quote":"Please know that if you are being charged for these products or offered these products outside of a clinical trial, you are likely being deceived and offered a product illegally.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"C3","text":"Check that you understand the entire process and known risks before signing","scope":"treatment_type","source":{"url":"https://www.fda.gov/safety/medical-product-safety-information/public-safety-alert-due-marketing-unapproved-stem-cell-and-exosome-products","host":"fda.gov","quote":"Make sure you understand the entire process and known risks before you sign.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"C4","text":"Ask the study sponsor for the clinical investigator's brochure, which covers safety and effectiveness","scope":"treatment_type","source":{"url":"https://www.fda.gov/safety/medical-product-safety-information/public-safety-alert-due-marketing-unapproved-stem-cell-and-exosome-products","host":"fda.gov","quote":"You also can ask the study sponsor for the clinical investigator’s brochure, which includes a short description of the product and information about its safety and effectiveness.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"C5","text":"Confirm the surgeon is trained and experienced in the exact procedure you are considering, not just in surgery generally","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Verify that the surgeon is trained and experienced in performing the procedure you are considering.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-13","next_check_at":"2027-11-13","version":1},"red_flags":{"status":"ok","items":[{"id":"F1","text":"The offer claims the product treats Alzheimer's disease, though it is not approved for that","scope":"procedure","source":{"url":"https://www.fda.gov/vaccines-blood-biologics/consumers-biologics/important-patient-and-consumer-information-about-regenerative-medicine-therapies?","host":"fda.gov","quote":"Regenerative medicine therapies have not been approved to treat any neurological disorder, such as multiple sclerosis, amyotrophic lateral sclerosis (ALS; Lou Gehrig’s disease), Alzheimer’s disease, Parkinson’s disease, epilepsy, or stroke.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"F2","text":"A clinic charges for the product outside any clinical trial","scope":"treatment_type","source":{"url":"https://www.fda.gov/vaccines-blood-biologics/consumers-biologics/important-patient-and-consumer-information-about-regenerative-medicine-therapies?","host":"fda.gov","quote":"Please know that if you are being charged for these products or offered these products outside of a clinical trial, you are likely being deceived and offered a product illegally.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"F3","text":"Marketing calls the product safe and effective though it lacks adequate study","scope":"treatment_type","source":{"url":"https://www.fda.gov/vaccines-blood-biologics/consumers-biologics/important-patient-and-consumer-information-about-regenerative-medicine-therapies?","host":"fda.gov","quote":"These regenerative medicine products have risks but are often illegally marketed by clinics as being safe and effective for the treatment of a wide range of diseases or conditions, even though they haven’t been adequately studied under an IND to demonstrate the claims of safety and effectiveness.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"F4","text":"The provider asks you to sign before explaining the process and known risks","scope":"treatment_type","source":{"url":"https://www.fda.gov/safety/medical-product-safety-information/public-safety-alert-due-marketing-unapproved-stem-cell-and-exosome-products","host":"fda.gov","quote":"Make sure you understand the entire process and known risks before you sign.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}}],"checked_at":"2026-11-13","next_check_at":"2027-11-13","version":1},"warning_signs":{"status":"missing","reason":"not_collected"},"take_home":{"status":"ok","items":[{"id":"T1","text":"Home doctor needs the clinic's follow-up recommendations in a written discharge summary","document":"discharge summary","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"When you have treatment abroad, you must ask the treatment provider for their follow-up recommendations documented within a written discharge summary in English.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T2","text":"Ask for copies of all prescriptions before you leave","document":"prescription copies","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Remember to ask for copies of all your treatment records, including prescriptions, scans and x-rays before you leave.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T3","text":"Home doctor needs the dates for required blood tests and follow-up appointments","document":"written aftercare plan","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"This should include any medication and doses, as well as any dates that blood tests and follow-up appointments must be carried out.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-13","next_check_at":"2027-11-13","version":1}},"parsed_details":{"procedure_type":"therapy","fields":{"anesthesia":["none","local"],"back_to_work_days":{"min":3,"max":7,"unit":"days","qualifier":"Most patients are retired; return to usual activities depends on route and post-procedure headache or fatigue."},"complication_rate_pct":{"min":10,"max":30,"unit":"percent","qualifier":"Any adverse event within 30 days, mostly transient headache, fever, back pain; serious events under 2%"},"contraindications":["Active infection","Active or past malignancy","Severe dementia","Bleeding disorders or anticoagulant therapy","Pregnancy or breastfeeding","Severe cardiac, renal or hepatic disease","Immunosuppression","Allergy to product components","Unstable psychiatric or medical condition"],"days_in_clinic":{"min":2,"max":5,"unit":"nights","qualifier":"Nights until post-dose observation and flight clearance; longer if headache persists."},"diagnostic_duration_minutes":null,"diagnostic_preparation":null,"diagnostic_referral_needed":null,"diagnostic_result_time_hours":null,"exercise_resume_weeks":{"min":1,"max":2,"unit":"weeks","qualifier":"Light activity resumes first; strenuous exercise waits until puncture-site and symptom resolution."},"final_result_months":{"min":3,"max":12,"unit":"months","qualifier":"Trials assess cognitive outcomes at 3-12 months; no proven effect."},"fly_home_after_days":{"min":2,"max":5,"unit":"days","qualifier":"After intrathecal dosing, clearance depends on headache resolution and clinician assessment."},"follow_up_visits":[{"purpose":"wound_check","after":{"min":1,"max":7,"unit":"days","qualifier":"Check for headache, fever or puncture-site problems."},"requirement":"routine"},{"purpose":"assessment","after":{"min":30,"max":90,"unit":"days","qualifier":"Cognitive testing such as MMSE or MoCA."},"requirement":"routine"},{"purpose":"result_review","after":{"min":90,"max":180,"unit":"days","qualifier":"Repeat cognitive testing and possible imaging."},"requirement":"routine"}],"indications":["Early-stage Alzheimer's disease","Mild cognitive impairment with Alzheimer's pathology"],"main_risks":["Post-lumbar puncture headache, back pain or low-grade fever","Infection, immune or allergic reactions, and route-related events (intrathecal, intravenous).","Unregulated clinics may use poorly characterized, contaminated or unproven products.","Theoretical abnormal cell growth; not shown in Alzheimer's trials."],"pain":"Mild and brief: lumbar puncture or IV site discomfort. Post-puncture headache, back pain or low-grade fever can occur for 1-3 days.","preparation":["Neurology review of diagnosis and stage","Baseline MMSE or MoCA testing","Brain MRI or CT review","Blood tests and infection screening","Review and adjust anticoagulants","Medication list reviewed","Caregiver or legal guardian consent"],"recovery_timeline":[{"phase":"Day 0-1","description":"Cell administration followed by observation for reactions, headache or fever.","restrictions":["Lie flat if intrathecal","Avoid driving","Stay hydrated"]},{"phase":"Days 2-7","description":"Mild fatigue or headache may settle; monitoring of neurological status continues.","restrictions":["No strenuous activity","Caregiver supervision"]},{"phase":"Weeks 2-4","description":"Return to normal routine; early follow-up checks.","restrictions":["Report fever, severe headache or new neurological symptoms"]},{"phase":"Months 3-6","description":"Cognitive reassessment to evaluate any change.","restrictions":[]}],"rehabilitation_days":{"min":3,"max":7,"unit":"days","qualifier":"Time to ordinary function after administration; cognitive rehabilitation, if used, continues separately."},"result_longevity":"No proven benefit or durability has been established. Any reported effect in trials is variable and often transient, with some clinics repeating courses after 3-6 months.","revision_rate_pct":{"min":0,"max":0,"unit":"percent","qualifier":"No corrective revision is typical; repeat dosing is counted under sessions or stages."},"scars":"No visible scar; only a small needle puncture mark at the lumbar or IV site. If cells are harvested by liposuction or marrow aspiration, a tiny puncture mark remains.","sessions_or_stages":{"sessions":{"min":1,"max":3,"unit":"visits","qualifier":"Usually one course of IV or intrathecal doses in one stay; some clinics repeat after 3-6 months."},"stages":[{"code":"assessment_screening","label":"Assessment and screening","after":{"min":0,"max":0,"unit":"days","qualifier":"Done on arrival before treatment."}},{"code":"cell_administration","label":"IV or intrathecal cell administration","after":{"min":1,"max":3,"unit":"days","qualifier":"Doses given within one stay."}},{"code":"repeat_course","label":"Optional repeat course","after":{"min":90,"max":180,"unit":"days","qualifier":"Only if the clinic protocol repeats dosing."}}],"qualifier":"Typical protocol is one course within a single stay."},"success":{"metric":null,"value":null,"unit":null,"horizon":null,"population":"Adults with mild Alzheimer's or mild cognitive impairment in small early-phase trials","evidence_status":"not_proven"},"techniques":[{"name":"Intravenous mesenchymal stem cell infusion","suits_whom":"Early-stage or mild cognitive impairment patients preferring a less invasive route.","recovery":"Same-day discharge; mild fever or fatigue for 1-2 days."},{"name":"Intrathecal stem cell injection","suits_whom":"Patients in trials seeking direct delivery to cerebrospinal fluid.","recovery":"Rest 24 hours; possible headache for 1-3 days."},{"name":"Intranasal stem cell delivery","suits_whom":"Experimental option for mild disease avoiding needles.","recovery":"No downtime; minimal local irritation."}],"treatment_conditions":["outpatient"],"treatment_duration_hours":{"min":2,"max":6,"unit":"hours","qualifier":"Infusion or lumbar puncture plus several hours of post-dose observation per session."},"initial_assessment_documents":["Neurologist report with Alzheimer's diagnosis","Brain MRI or CT report","MMSE or MoCA cognitive test results","Amyloid or tau PET report (if available)","Recent blood tests with infection screening","List of current dementia medications"],"travel_trips":{"min":1,"max":1,"one_trip_possible":true,"qualifier":"One trip covers the single-stay course; repeat courses need extra trips."},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Check whether the treatment is approved for Alzheimer's disease","scope":"procedure","source":{"url":"https://www.fda.gov/vaccines-blood-biologics/consumers-biologics/consumer-alert-regenerative-medicine-products-including-stem-cells-and-exosomes","host":"fda.gov","quote":"None of these products have been approved to treat any neurological disorder, such as multiple sclerosis, amyotrophic lateral sclerosis (ALS; Lou Gehrig’s disease), Alzheimer’s disease, Parkinson’s disease, epilepsy, or stroke.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"C2","text":"Check that the product is offered only within a clinical trial, since charges outside one suggest an illegal product","scope":"treatment_type","source":{"url":"https://www.fda.gov/vaccines-blood-biologics/consumers-biologics/important-patient-and-consumer-information-about-regenerative-medicine-therapies?","host":"fda.gov","quote":"Please know that if you are being charged for these products or offered these products outside of a clinical trial, you are likely being deceived and offered a product illegally.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"C3","text":"Check that you understand the entire process and known risks before signing","scope":"treatment_type","source":{"url":"https://www.fda.gov/safety/medical-product-safety-information/public-safety-alert-due-marketing-unapproved-stem-cell-and-exosome-products","host":"fda.gov","quote":"Make sure you understand the entire process and known risks before you sign.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"C4","text":"Ask the study sponsor for the clinical investigator's brochure, which covers safety and effectiveness","scope":"treatment_type","source":{"url":"https://www.fda.gov/safety/medical-product-safety-information/public-safety-alert-due-marketing-unapproved-stem-cell-and-exosome-products","host":"fda.gov","quote":"You also can ask the study sponsor for the clinical investigator’s brochure, which includes a short description of the product and information about its safety and effectiveness.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"C5","text":"Confirm the surgeon is trained and experienced in the exact procedure you are considering, not just in surgery generally","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Verify that the surgeon is trained and experienced in performing the procedure you are considering.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-13","next_check_at":"2027-11-13","version":1},"red_flags":{"status":"ok","items":[{"id":"F1","text":"The offer claims the product treats Alzheimer's disease, though it is not approved for that","scope":"procedure","source":{"url":"https://www.fda.gov/vaccines-blood-biologics/consumers-biologics/important-patient-and-consumer-information-about-regenerative-medicine-therapies?","host":"fda.gov","quote":"Regenerative medicine therapies have not been approved to treat any neurological disorder, such as multiple sclerosis, amyotrophic lateral sclerosis (ALS; Lou Gehrig’s disease), Alzheimer’s disease, Parkinson’s disease, epilepsy, or stroke.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"F2","text":"A clinic charges for the product outside any clinical 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adequately studied under an IND to demonstrate the claims of safety and effectiveness.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"F4","text":"The provider asks you to sign before explaining the process and known risks","scope":"treatment_type","source":{"url":"https://www.fda.gov/safety/medical-product-safety-information/public-safety-alert-due-marketing-unapproved-stem-cell-and-exosome-products","host":"fda.gov","quote":"Make sure you understand the entire process and known risks before you sign.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}}],"checked_at":"2026-11-13","next_check_at":"2027-11-13","version":1},"warning_signs":null,"take_home":{"status":"ok","items":[{"id":"T1","text":"Home doctor needs the clinic's follow-up recommendations in a written discharge summary","document":"discharge 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stamping","source":{"url":"https://www.gov.uk/foreign-travel-advice/china/entry-requirements","host":"gov.uk","quote":"To enter China, your passport must have an ‘expiry date’ at least 6 months after the date you arrive and 2 blank pages for visas and stamping.","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}},{"id":"V4","item":"passport_validity","audience":"us","volatile":true,"text":"A US passport must have at least six months of validity remaining to enter China","source":{"url":"https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/China.html","host":"travel.state.gov","quote":"Your passport must have at least six months' validity remaining.","tier":"official_travel","fetched_at":"2026-11-11","http_status":403}},{"id":"V5","item":"medicines","audience":"us","volatile":false,"text":"Carry prescription medication for China in its original packaging, along with the prescription","source":{"url":"https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/China.html","host":"travel.state.gov","quote":"Carry prescription medication in original packaging, along with the prescription.","tier":"official_travel","fetched_at":"2026-11-11","http_status":403}},{"id":"V6","item":"hospital_payment","audience":"all","volatile":false,"text":"Hospitals in China often require payment in cash or by mobile payment app before treatment, including emergency cases","source":{"url":"https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/China.html","host":"travel.state.gov","quote":"Payment in cash or via mobile payment app for services is often required prior to treatment, including emergency cases.","tier":"official_travel","fetched_at":"2026-11-11","http_status":403}},{"id":"V7","item":"emergency_number","audience":"all","volatile":false,"text":"Call 120 and ask for an ambulance in China","source":{"url":"https://www.gov.uk/foreign-travel-advice/china/health","host":"gov.uk","quote":"Call 120 and ask for an ambulance.","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-11","next_check_at":"2026-12-11","version":1},"other_countries_with_page":["colombia","india","italy","japan","mexico","republic-of-korea","spain","thailand","turkey","ukraine"]},"often_combined_with":{"status":"missing","reason":"not_collected"},"reviews":{"avg_rating":{"status":"missing","reason":"not_collected"},"count":{"status":"missing","reason":"not_collected"},"scope":"clinic","rating_scale":5,"pros":{"status":"missing","reason":"not_collected"},"cons":{"status":"missing","reason":"not_collected"}},"current":{"seo_text":"<p class=\"bm-h1-lead\">Stem cell therapy for alzheimer's disease in China costs _op_1430_price_from_ to _op_1430_price_to_. Bookimed lists 2 stem cell therapy for alzheimer's disease clinics in China, in Qionghai and Qinhuangdao.</p>","faq":{"status":"missing","reason":"not_collected"},"h2":[{"text":"Як це працює","kind":"content"},{"text":"Яка вартість лікування хвороби Альцгеймера стовбуровими клітинами в Китаї?","kind":"content"},{"text":"Пропозиції з лікування хвороби Альцгеймера стовбуровими клітинами в Китаї — листопад 2026","kind":"content"},{"text":"Дізнайтеся про найкращі клініки з лікування хвороби Альцгеймера стовбуровими клітинами у Китаї: 2 перевірені клініки та ціни","kind":"content"},{"text":"Огляд процедури Лікування хвороби Альцгеймера стовбуровими клітинами в Китаї","kind":"content"},{"text":"Відеоісторії пацієнтів Bookimed","kind":"content"},{"text":"Поділитися цим контентом","kind":"content"},{"text":"Отримати безкоштовну консультацію","kind":"content"}]},"placeholders":{"price_from":"{{price_from}}","clinics_count":"{{clinics_count}}","cities_count":"{{cities_count}}","savings_pct":"{{savings_pct}}","data_date":"{{data_date}}"},"legal":{"restricted_markets":{"status":"missing","reason":"not_collected"}},"conflicts":[{"field":"medical.hospital_nights","chosen":"offers","offers":30,"parsed_details":{"min":2,"max":5}}]}